Reflections on Cardiovascular Risk Stratification and Prevention

Reflections on cardiovascular risk estimates in primary prevention.

Cardiovascular risk stratification in familial hypercholesterolaemia

Familial hypercholesterolaemia (FH) is a common autosomal-dominant disorder in most European countries. Patients with FH are characterised by a raised level of low-density lipoprotein cholesterol and a high risk of premature coronary heart disease (CHD). Currently there is no consensus regarding the clinical utility to predict future coronary events or testing for the presence of subclinical at...

Ambulatory blood pressure for cardiovascular risk stratification.

Ambulatory blood pressure (ABP) monitoring is increasingly recognized as a valuable tool to refine prediction of cardiovascular risk related to blood pressure (BP).1 After the first landmark study published by Perloff and colleagues 24 years ago,2 several longitudinal event-based studies provided unequivocal evidence of an independent association between ABP and risk of cardiovascular disease. ...

Cardiovascular Risk Stratification: From Phenotype to Genotype?

DOI: 10.5935/abc.20180010 Cardiovascular risk scores, such as the Framingham score, have been strongly recommended by clinical guidelines on the assessment of cardiovascular risk.1 However, several studies have shown limitations for their use,2,3 particularly in patients at intermediate risk, young patients with a definite family history, and women. Among different tools aimed at improving risk...

[Secondary prevention program: impact on cardiovascular risk].

The aims of this study were to determine the effect of a secondary prevention program on the treatment and control of coronary risk factors and to assess whether it improves functional capacity. The study involved 401 patients with coronary heart disease (mean age 57.1 years; 89% men). Clinical and anthropometric data, including blood pressure, were recorded, and electrocardiography, laboratory...